Robert Francis Prevost was born on September 14, 1955, in Chicago, Illinois, to Louis Marius Prevost, of French and Italian descent, and Mildred Martínez, of Spanish descent. He has two brothers, Louis Martín and John Joseph.

He spent his childhood and adolescence with his family and studied first at the Minor Seminary of the Augustinian Fathers and then at Villanova University in Pennsylvania, where in 1977 he earned a Degree in Mathematics and also studied Philosophy.

On September 1 of the same year, Prevost entered the novitiate of the Order of Saint Augustine (O.S.A.) in Saint Louis, in the Province of Our Lady of Good Counsel of Chicago, and made his first profession on September 2, 1978. On August 29, 1981, he made his solemn vows.

The future Pontiff received his theological education at the Catholic Theological Union in Chicago. At the age of 27, he was sent by his superiors to Rome to study Canon Law at the Pontifical University of Saint Thomas Aquinas (Angelicum).

In Rome, he was ordained a priest on June 19, 1982, at the Augustinian College of Saint Monica by Archbishop Jean Jadot, then pro-president of the Secretariat for Non-Christians, which later became the Pontifical Council for Interreligious Dialogue and then the Dicastery for Interreligious Dialogue.

Prevost obtained his licentiate in 1984 and the following year, while preparing his doctoral thesis, was sent to the Augustinian mission in Chulucanas, Piura, Peru (1985-1986). In 1987, he defended his doctoral thesis on "The Role of the Local Prior in the Order of Saint Augustine" and was appointed vocation director and missions director of the Augustinian Province of “Mother of Good Counsel” in Olympia Fields, Illinois (USA).

Mission in Peru

The following year, he joined the mission in Trujillo, also in Peru, as director of the joint formation project for Augustinian candidates from the vicariates of Chulucanas, Iquitos, and Apurímac.

Over the course of eleven years, he served as prior of the community (1988-1992), formation director (1988-1998), and instructor for professed members (1992-1998), and in the Archdiocese of Trujillo as judicial vicar (1989-1998) and professor of Canon Law, Patristics, and Moral Theology at the Major Seminary “San Carlos y San Marcelo.” At the same time, he was also entrusted with the pastoral care of Our Lady Mother of the Church, later established as the parish of Saint Rita (1988-1999), in a poor suburb of the city, and was parish administrator of Our Lady of Monserrat from 1992 to 1999.

Prior General of the Augustinian Order

In 1999, he was elected Provincial Prior of the Augustinian Province of “Mother of Good Counsel” in Chicago, and two and a half years later, the ordinary General Chapter of the Order of Saint Augustine, elected him as Prior General, confirming him in 2007 for a second term.

In October 2013, he returned to his Augustinian Province in Chicago, serving as director of formation at the Saint Augustine Convent, first councilor, and provincial vicar—roles he held until Pope Francis appointed him on November 3, 2014, as Apostolic Administrator of the Peruvian Diocese of Chiclayo, elevating him to the episcopal dignity as Titular Bishop of Sufar. 

He entered the Diocese on November 7, in the presence of Apostolic Nuncio James Patrick Green, who ordained him Bishop just over a month later, on December 12, the Feast of Our Lady of Guadalupe, in the Cathedral of Saint Mary.

Bishop of Chiclayo, Peru, from 2015 to 2023

On September 26, 2015, he was appointed Bishop of Chiclayo by Pope Francis. In March 2018, he was elected second vice-president of the Peruvian Episcopal Conference, where he also served as a member of the Economic Council and president of the Commission for Culture and Education.

In 2019, Pope Francis appointed him a member of the Congregation for the Clergy (July 13, 2019), and in 2020, a member of the Congregation for Bishops (November 21). Meanwhile, on April 15, 2020, he was also appointed Apostolic Administrator of the Peruvian Diocese of Callao.

Prefect of the Dicastery for Bishops

On January 30, 2023, the Pope called him to Rome as Prefect of the Dicastery for Bishops and President of the Pontifical Commission for Latin America, promoting him to the rank of Archbishop. 

Created Cardinal in 2023

Pope Francis created him Cardinal in the Consistory of September 30, 2023, and assigned him the Diaconate of Saint Monica. He officially took possession of his titular church on January 28, 2024. 

As head of the Dicastery, he participated in the Pope's most recent Apostolic Journeys and in both the first and second sessions of the 16th Ordinary General Assembly of the Synod of Bishops on synodality, held in Rome from October 4 to 29, 2023, and from October 2 to 27, 2024, respectively.

Meanwhile, on October 4, 2023, Pope Francis appointed him as a member of the Dicasteries for Evangelization (Section for First Evangelization and New Particular Churches), for the Doctrine of the Faith, for the Eastern Churches, for the Clergy, for Institutes of Consecrated Life and Societies of Apostolic Life, for Culture and Education, for Legislative Texts, and of the Pontifical Commission for the Vatican City State.

Finally, on 6 February 2023, the Holy Father promoted him to the Order of Bishops, granting him the title of the Suburbicarian Church of Albano.

Universal Pastor of the Church

On 8 May 2025 his election to the Pontificate. On 18 May 2025: the solemn beginning of his ministry as the universal Pastor of the Church.